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Alfuzosin + Dutasteride

Uses of Alfuzosin + Dutasteride

  • Alfuzosin + Dutasteride is used to manage the symptoms of benign prostatic hyperplasia (BPH), a non-cancerous enlargement of the prostate gland in men. The medicine belongs to the group of alpha-blockers and 5-alpha reductase inhibitors.

Side effects of Alfuzosin + Dutasteride

  • Impotence (erectile dysfunction)

  • Decreased libido

  • Ejaculation disorders (decreased volume of ejaculate)

  • Breast enlargement or tenderness

  • Dizziness

How Alfuzosin + Dutasteride works

  • Alfuzosin is an alpha-blocker that works by relaxing the muscles in the prostate gland and bladder neck. This helps to improve urine flow by reducing the resistance to the passage of urine.

  • Dutasteride is a 5-alpha reductase inhibitor that inhibits an enzyme, 5-alpha reductase, which converts testosterone to dihydrotestosterone (DHT). This leads to decreased DHT levels, which reduces the size of an enlarged prostate and relieves symptoms.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Alfuzosin + Dutasteride is available in the form of oral tablets.

Age and Dose Restrictions

  • Alfuzosin + Dutasteride is used by adult men and is not meant for use in women or children.

Contraindications

  • This medicine should not be used in patients who have a known allergy to either alfuzosin, dutasteride, or any other components of this medication.

Other Medications to Avoid With This Medicine

  • Alfuzosin + Dutasteride may interact with potent inhibitors of cytochrome P4503A4 (such as ketoconazole, itraconazole, and ritonavir), other alpha-blockers (like prazosin and tamsulosin), and erectile dysfunction medications (such as sildenafil and tadalafil).

Overdose and Missed Dose

  • An overdose of Alfuzosin + Dutasteride may result in severe hypotension (low blood pressure). If you suspect an overdose, seek immediate medical help.

  • If you miss a dose of this medicine, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and continue with your regular schedule.

Management of Side Effects

  • Most side effects are temporary and generally harmless and resolve after stopping this medicine. However, if you experience any severe side effects or worsening symptoms, please consult your doctor.

  • To manage dry mouth, stay well hydrated, chew sugar-free gum, or suck on sugar-free hard candies.

  • If the medication causes insomnia, avoid taking it close to bedtime.

Use in Driving and Operating Machinery

  • Alfuzosin + Dutasteride can cause dizziness, especially when starting the medication. Therefore, caution should be taken when driving or operating machinery until you know how this medicine affects you.

Use in Pregnancy and Lactation

  • Alfuzosin + Dutasteride is not recommended for use in women. It can pose significant risks to a developing foetus when used during pregnancy and is therefore contraindicated.

Caution in Other Conditions

  • People with a history of liver disease should be cautious while using this medication due to the potential for increased side effects.

  • Caution is also advised for individuals known to have orthostatic hypotension (a sudden fall in blood pressure when standing).

Special Dietary and Lifestyle Recommendation

  • Regular physical activity can help increase urinary flow and relieve some symptoms of BPH.

  • Limiting beverages in the evening can help reduce the need for frequent urination during the night.

  • Avoiding or limiting caffeine and alcohol may help reduce symptoms, as they can increase urine production and irritate the bladder.

Frequently asked questions

No, it is not a steroid. It consists of two active ingredients - Alfuzosin, which is an alpha-blocker, and Dutasteride, which is a 5-alpha reductase inhibitor.

This medicine usually does not affect sleep. However, if you experience sleep disturbances after starting this medication, consult your doctor promptly.

One of the common side effects of this medication is decreased libido. However, there is no direct evidence of an impact on long-term fertility. If you have any concerns about this matter, it would be best to consult your doctor.

There are no specific dietary restrictions that need to be followed while taking this medicine.

Yes, it is usually safe to take the medicine daily as per your doctor's prescribed dosage.

The time taken for this medicine to show its effect may vary depending on individual body responses. Your doctor would be the best person to provide this information based on your specific situation.

This medicine requires a doctor's prescription and is not typically available over the counter.

Terms & Conditions


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